Saving lives by stepping up Africa's response to sepsis

Saving lives by stepping up Africa's response to sepsis

Sub-Saharan African ConsorTium for the Advancement of Innovative Research and Care in SepsisSub-Saharan African ConsorTium for the
Advancement of Innovative Research
and Care in Sepsis
Pictures & Impressions
Pictures & Impressions
Sub-Saharan African ConsorTium for the Advancement of Innovative Research and Care in Sepsis
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Sepsis

is life-threatening organ dysfunction caused by a dysregulated host response to infection.

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13.7 million

Number of people worldwide whose cause of death was sepsis in 2019.

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30% of deaths
from sepsis

Sub-Saharan Africa bears the greatest burden of sepsis worldwide.

Director and Chief Scientific Officer (CSO)
Dr. Shevin Jacob
Walimu, Kampala, Uganda

Co-Directors
Professor Dr. Konrad Reinhart
Charité – Universitätsmedizin Berlin, Germany
Professor Dr. Torsten Feldt
Heinrich-Heine-Universität Düsseldorf, Germany

Deputy CSO
Dr. Tafese Tufa
Arsi University, Asella, Ethiopa

Founding Director and Senior Strategic Advisor

Dr. Nathan Kenya-Mugisha
Walimu, Kampala, Uganda

Our Program

With eight African and two German partner institutions, STAIRS aims to save lives through innovative sepsis research in sub-Saharan Africa. We leverage our existing networks and seek new partners to …

  • address vital knowledge gaps in sepsis epidemiology, diagnosis and care quality
  • strengthen research capacity
  • translate emerging evidence to policy

Our Team


1
Sierra Leone
Njala University, Bo

2
Ghana
Komfo Anokye Teaching Hospital, Kumasi

3
Nigeria
University of Nigeria Teaching Hospital, Enugu

4
Ethiopia
Arsi University, Asella

5
Uganda
Walimu, Kampala

6
Uganda
Makerere University - Infectious Diseases Institute, Kampala

7
Democratic Republic of the Congo
Catholic University of Bukavu, Bukavu

8
Mozambique
Instituto Nacional de Saúde, Maputo

9
Germany
Charité - Universitätsmedizin Berlin, Berlin

10
Germany
University Hospital of Heinrich-Heine University, Düsseldorf

Our Areas of Work

High-quality research in Sub-Saharan Africa - Icon
High-quality research in Sub-Saharan Africa
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High-quality research in Sub-Saharan Africa
The research initiative encompasses five tasks aimed at enhancing the understanding of and response to sepsis in sub-Saharan Africa. STAIRS will:

Assess the burden of sepsis in the community.

Establish a multinational patient cohort of adults and children.

Refine and evaluate the role of an electronic quality improvement mobile application on in-hospital sepsis care.

Evaluate a novel comprehensive sepsis panel.

Evaluate the role of post-discharge strategies on survival.

Strengthening capacity for sepsis research and care - Icon
Strengthening capacity for sepsis research and care
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Strengthening capacity for sepsis research and care
Stairs will:

Sponsor early career researchers.

Build technical and institutional research capacity, including for clinical trials on sepsis.

Explore the use of telemedicine to improve clinical care.

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Networking inside and outside the consortium
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Networking inside and outside the consortium
STAIRS will:

Establish a robust sepsis research network across sub-Saharan Africa.

Strengthen sepsis programs and initiatives across sub-Saharan Africa.

Enable engagement between industry partners and policymakers.

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Policy engagement and research transfer
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Policy engagement and research transfer
STAIRS will:   

Align with the WHO resolution “Improving the prevention, diagnosis and clinical management of sepsis”.

Translate evidence to sepsis-relevant policies across the network.

Approach stakeholder engagement across the network holistically and inclusively.


Our Partners

To increase impact, STAIRS will collaborate with external organizations, institutions and industry partners.

Recent Activities

News
Event

Mozambique STAIRS Team Commemorates World Sepsis Day

Strengthening Sepsis Awareness, Early Detection and Treatment in Mozambique and Across Sub-Saharan Africa The Mozambique team of the Sub-Saharan Africa Consortium for the Advancement of...
Oct 16, 2026

Mozambique STAIRS Team Commemorates World Sepsis Day

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Strengthening Sepsis Awareness, Early Detection and Treatment in Mozambique and Across Sub-Saharan Africa

The Mozambique team of the Sub-Saharan Africa Consortium for the Advancement of Innovative Research and Care in Sepsis (STAIRS) joined the global community in commemorating World Sepsis Day 2026, observed annually on 13 September, through a series of awareness-raising and scientific engagement activities aimed at improving the prevention, early recognition and treatment of sepsis.

In collaboration with the Instituto Nacional de Saúde (INS) Mozambique, the team organized an educational webinar and developed two informative infographics to increase public understanding of sepsis, highlight its significant public health burden and encourage timely medical intervention.

These activities represent important milestones in the Mozambique STAIRS team’s ongoing commitment to advancing sepsis research, strengthening healthcare capacity and promoting evidence-informed approaches to improving patient outcomes.

Advancing Scientific Dialogue Through a World Sepsis Day Webinar

As part of the commemoration, the Instituto Nacional de Saúde hosted a webinar on 14 September 2026, under the theme:

“World Sepsis Day: Together for a Timely and Effective Response.”

Conducted virtually through Microsoft Teams, the webinar brought together researchers, medical practitioners and healthcare professionals, including physicians from major healthcare facilities across Mozambique.

The discussions focused on the challenges associated with sepsis prevention, early detection and effective treatment, while highlighting opportunities to strengthen healthcare responses at national and regional levels.

Expert Presentations and Discussions

The webinar featured presentations from healthcare and research professionals with expertise in infectious diseases, public health and sepsis management.

Dr. Virginia Lara Evaristo delivered a presentation titled “Detection and Treatment of Sepsis: Challenges for a Timely and Effective Response.”

Her presentation addressed critical challenges in recognizing and managing sepsis, emphasizing the importance of early identification, timely clinical intervention and effective healthcare responses.

Dr. Celso Monjane presented on “The Burden of Sepsis Globally, Regionally, and in Mozambique: Impact and Public Health Priorities.”

His presentation highlighted the burden of sepsis across different geographical contexts, drawing attention to its implications for public health and the need to prioritize prevention, surveillance and improved clinical management.

The webinar was moderated by Dr. Ivalda Macicame, a Research Physician at the Instituto Nacional de Saúde and Principal Investigator of the multicenter STAIRS project in Mozambique.

Through these presentations and discussions, the webinar helped inform stakeholders about sepsis and stimulated interest in greater collaboration to address the condition.

Raising Public Awareness Through Educational Infographics

Recognizing the importance of accessible health information, the Mozambique STAIRS team also developed and disseminated two educational infographics in Portuguese to support public awareness and understanding of sepsis.

The materials were designed to communicate essential information about the condition, its global and regional burden, warning signs and preventive measures.

Infographic 1: Sepsis in Numbers – Understanding the Global and Regional Burden

The first infographic, titled “A Sepse em Números” (Sepsis in Numbers), highlights the substantial burden of sepsis worldwide, with particular attention to Sub-Saharan Africa and Mozambique.

Drawing on global and regional sepsis reports, the infographic presents key statistics illustrating the scale of the public health challenge.

It highlights estimates of approximately 166 million sepsis cases and 21 million sepsis-related deaths annually worldwide, as reported in the campaign material. It also draws attention to the disproportionate burden experienced by low- and middle-income countries.

For Sub-Saharan Africa, the infographic highlights reported sepsis incidence ranging from 1,600 to 4,000 cases per 100,000 inhabitants, alongside challenges associated with hospital mortality, disease surveillance and limited availability of reliable data.

In Mozambique, the material emphasizes the contribution of sepsis to maternal and neonatal mortality, as well as the importance of strengthening early recognition and timely healthcare interventions.

These statistics reinforce the need for sustained investment in sepsis research, surveillance, prevention and improved access to quality healthcare.

Infographic 2: Recognizing Sepsis and Taking Action

The second infographic, developed under the theme “Sepsis at Any Age, Anywhere,” focuses on improving public understanding of sepsis, recognizing warning signs and promoting preventive action.

It explains that sepsis is a life-threatening condition that occurs when the body’s response to an infection causes organ dysfunction.

The infographic highlights infections that may lead to sepsis, including pneumonia, urinary tract infections, meningitis and skin infections.

It also outlines important warning signs, such as:

  • Fever or abnormally low body temperature.
  • Rapid breathing or difficulty breathing.
  • Confusion, altered mental status or unusual drowsiness.
  • Increased heart rate.
  • Low blood pressure.
  • Extreme weakness or a feeling of faintness.

The material emphasizes the importance of seeking immediate medical attention when sepsis is suspected, as early recognition and appropriate treatment are essential to improving survival.

In addition, it promotes preventive measures, including vaccination, proper hand hygiene, appropriate antibiotic use, timely healthcare-seeking and additional protection for vulnerable populations.

Together, the two infographics provide valuable educational resources for healthcare professionals, community members and other stakeholders involved in sepsis prevention and management.

Strengthening Collaboration and Public Health Engagement

The World Sepsis Day activities provided an opportunity for the Mozambique STAIRS team to engage healthcare professionals, researchers and the wider public in discussions about one of the most pressing challenges affecting healthcare systems.

By combining scientific dialogue with accessible public health communication, the team contributed to greater awareness of the importance of preventing infections, recognizing sepsis early and ensuring timely and appropriate treatment.

The webinar also encouraged professional engagement and collaboration, supporting broader efforts to improve knowledge and strengthen responses to sepsis in Mozambique.

These activities reflect the value of coordinated research, capacity building and knowledge-sharing initiatives in addressing sepsis across Sub-Saharan Africa.

A Significant Milestone for STAIRS Mozambique

The successful organization of the World Sepsis Day webinar and dissemination of educational infographics mark important milestones in the Mozambique STAIRS team’s awareness and stakeholder engagement activities.

Through continued collaboration with national health institutions, researchers, healthcare professionals and international partners, STAIRS seeks to contribute to innovative approaches that strengthen sepsis research and care.

The Mozambique team’s participation in World Sepsis Day 2026 demonstrates its commitment to advancing knowledge, promoting early diagnosis and supporting improved clinical responses to sepsis.

Together, through research, awareness, collaboration and timely action, we can strengthen the response to sepsis and help save lives.


Related Resources

World Sepsis Day 2026 Webinar

Theme: Together for a Timely and Effective Response
Date: 14 September 2026
Format: Virtual – Microsoft Teams
Organized by: Instituto Nacional de Saúde, Mozambique

Awareness Materials

  • Infographic 1: Sepsis in Numbers – A Global Reality That Demands Action.
  • Infographic 2: World Sepsis Day – Understanding Sepsis, Recognizing Warning Signs and Prevention.

The awareness materials were developed and disseminated as part of the Mozambique STAIRS team’s World Sepsis Day 2026 commemoration activities.

News
Event

STAIRS Consortium Holds 3rd Annual Meeting

The STAIRS Consortium convened its 3rd Annual Meeting in Maputo, Mozambique, from 17–21 November 2025, bringing together representatives from all participating countries alongside inv...
Nov 21, 2025

STAIRS Consortium Holds 3rd Annual Meeting

Maputo, Mozambique

The STAIRS Consortium convened its 3rd Annual Meeting in Maputo, Mozambique, from 17–21 November 2025, bringing together representatives from all participating countries alongside invited experts and stakeholders committed to strengthening sepsis research and implementation.


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The STAIRS Consortium convened its 3rd Annual Meeting in Maputo, Mozambique, from 17–21 November 2025, bringing together representatives from all participating countries alongside invited experts and stakeholders committed to strengthening sepsis research and implementation.

The meeting attracted over 100 participants on the opening day alone, underscoring the strong engagement and shared commitment across the consortium. It provided a key opportunity to review progress on STAIRS implementation, exchange country experiences, and reflect on emerging lessons from ongoing activities across diverse health systems.

The official opening ceremony was led by Dr. Eduardo Samo Gudo, Director General of the National Institute of Health (NHI) Mozambique. In his address, he underscored the importance of collaboration and coordinated action in advancing efforts to combat sepsis, emphasizing that sustained teamwork remains central to achieving meaningful public health impact.

Beyond the formal proceedings, the meeting also showcased elements of Mozambican culture during the opening ceremony, adding a rich and unifying dimension to the event and reinforcing the spirit of regional solidarity.

A key feature of the program was the first expert roundtable discussion, which brought together leading specialists, including Dr. Shaving, to deliberate on implementation progress, scientific evidence, and strategic priorities for strengthening sepsis interventions within participating countries.

As host Principal Investigator for Mozambique, Dr. Ivalda Macicame provided an overview of the country’s implementation journey during her remarks. She highlighted progress made to date, shared practical field experiences, and reaffirmed Mozambique’s commitment to advancing the STAIRS agenda in close collaboration with consortium partners.

The meeting reaffirmed STAIRS as a critical platform for fostering cross-country learning, strengthening research-to-practice translation, and accelerating collective action against sepsis across the region.

News
Event

STAIRS Second Annual Consortium Meeting, January 13-17, 2025

We keep climbing! The second annual consortium meeting of the STAIRS consortium in Kumasi, Ghana, was graciously hosted from January 13-17, 2025, by STAIRS PI in Ghana Dr. Johna Adabie ...
Nov 14, 2025

STAIRS Second Annual Consortium Meeting, January 13-17, 2025

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The network comes together for the Second Annual consortium meeting in Kumasi, Ghana (January 2025)

We keep climbing! The second annual consortium meeting of the STAIRS consortium in Kumasi, Ghana, was graciously hosted from January 13-17, 2025, by STAIRS PI in Ghana Dr. Johna Adabie Appiah, together with his amazing team from Komfo Anokye Teaching Hospital. We were especially grateful to welcome the president of the Global Sepsis Alliance, Prof. Niranjan Tex Kissoon, and Dr. Janet Diaz from WHO in Geneva!

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Event

EIDM Training in DRC, July 2024

Completing the tour of the network, AFIDEP visited our DRC country team for Evidence-informed decision training in July....
Nov 14, 2025

EIDM Training in DRC, July 2024

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Completing the tour of the network, AFIDEP visited our DRC country team for Evidence-informed decision training in July.

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Event

EIDM Training in Ghana, July 2024

The Ghana STAIRS team was also visited by our partners from AFIDEP in July. Evidence-informed decision training!...
Nov 14, 2025

EIDM Training in Ghana, July 2024

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The Ghana STAIRS team was also visited by our partners from AFIDEP in July. Evidence-informed decision training!

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Event

EIDM Training in Ethiopia, July 1-5, 2024

Upwards and onwards! The STAIRS team in Ethiopia invited our partners from AFIDEP to the beautiful Rift Valley to conduct the evidence-informed decision training in July. The team broug...
Aug 07, 2024

EIDM Training in Ethiopia, July 1-5, 2024

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Upwards and onwards! The STAIRS team in Ethiopia invited our partners from AFIDEP to the beautiful Rift Valley to conduct the evidence-informed decision training in July. The team brought together a group of 19 stakeholders to strengthen capacity for translating sepsis research findings into policy in Ethiopia.

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